2010
$20,000
Melbourne University/Prof J Savige
Novel Chemical Treatments for Alport Syndrome
$20,000
Monash University/AProf Sharon Ricardo
Novel stem cell assays for Alports Syndrome
2011
$20,000
Melbourne University/Prof J Savige
Examining the effect of chemical chaperones in mice with X-linked and autosomal recessive Alport syndrome
$20,000
Melbourne University/Prof J Savige
Enlarging the LOVD COL4A3/COL4A4 Databases for autosomal Alport syndrome to improve diagnostic accuracy and predict renal failure
2012
$20,000
Monash University/AProf Sharon Ricardo
Kidney Stem Cell Lines for Alport syndrome
$5,000
Griffiths University/Dr Madeleine Peterson
Optimising genetic counseling support for individuals and families affected by Alport syndrome
$20,000
Melbourne University/Prof J Savige
Effect of COL4A5 mutations in induced pluripotent stem cells from X-linked Alport Syndrome – an in vitro model for evaluating new therapies
2013
$20,000
Monash University/Dr John Haynes & Prof Sharon Ricardo
Using induced pluripotent stem cell-derived podocytes to create an in vitro model of Alport Syndrome
2014
$20,000
Melbourne University/Prof J Savige
Correcting the mutation defect in Alport syndrome in human cell lines using the TALEN method: a potentially-curative treatment
$7,000
Royal Brisbane Womens Hospital/Dr Andrew Mallett
Next Generation Sequencing and Induced Pluripotent Stem Cell Applications in Genetic Renal Disease (Alport Syndrome Cohort)
$13,000
Childrens Hospital Westmead/AProf Steve Alexander
(associate of above)
University of Queensland/Prof Melissa Little
(associate of above)
$20,000
Melbourne University/Prof J Savige
Development of the Alport Foundation of Australia Patient Registry
2015
$20,000
Melbourne University/Prof J Savige
A clinical trial of a chemical chaperone, PBA, in X-linked Alport syndrome due to missense mutations
$20,000
Monash University/AProf Sharon Ricardo
Fate mapping kidney podocytes
2016
$17,360
Monash University/Dr John Haynes & Prof Sharon Ricardo
Dysregulation of focal adhesion kinase in Alport Syndrome patients
$20,000
Monash University/Profs Ricardo & Smyth
Generation of X-linked rodent models of Alport syndrome using CRISPR/Casmediated genome engineering
$15,000
Dr Hugh McCarthy
Utilising Whole Genome Sequencing to identify novel pathogenic mutations in patients with a clinical diagnosis of Alport Syndrome